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What is OASIS?

The Open Access Series of Imaging Studies (OASIS) is a project aimed at making MRI data sets of the brain freely available to the scientific community. By compiling and freely distributing MRI data sets, we hope to facilitate future discoveries in basic and clinical neuroscience. OASIS is made available by the Washington University Alzheimer’s Disease Research Center, Dr. Randy Buckner at the Howard Hughes Medical Institute (HHMI) at Harvard University, the Neuroinformatics Research Group (NRG) at Washington University School of Medicine, and the Biomedical Informatics Research Network (BIRN).

When publishing findings that benefit from OASIS data, please include the following grant numbers in the acknowledgements section and in the associated Pubmed Central submission: P50 AG05681, P01 AG03991, R01 AG021910, P50 MH071616, U24 RR021382, R01 MH56584.

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OASIS: Cross-sectional MRI Data in Young, Middle Aged, Nondemented and Demented Older Adults

Summary   This set consists of a cross-sectional collection of 416 subjects aged 18 to 96.  For each subject, 3 or 4 individual T1-weighted MRI scans obtained in single scan sessions are included.  The subjects are all right-handed and include both men and women.  100 of the included subjects over the age of 60 have been clinically diagnosed with very mild to moderate Alzheimer’s disease (AD).  Additionally, a reliability data set is included containing 20 nondemented subjects imaged on a subsequent visit within 90 days of their initial session.
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Actions   Browse: cross-sectional data  |  reliability data    Spreadsheet: csv  |  xls    Images: ftp  |  web services


OASIS: Longitudinal MRI Data in Nondemented and Demented Older Adults
Summary   This set consists of a longitudinal collection of 150 subjects aged 60 to 96. Each subject was scanned on two or more visits, separated by at least one year for a total of 373 imaging sessions. For each subject, 3 or 4 individual T1-weighted MRI scans obtained in single scan sessions are included. The subjects are all right-handed and include both men and women. 72 of the subjects were characterized as nondemented throughout the study. 64 of the included subjects were characterized as demented at the time of their initial visits and remained so for subsequent scans, including 51 individuals with mild to moderate Alzheimer’s disease. Another 14 subjects were characterized as nondemented at the time of their initial visit and were subsequently characterized as demented at a later visit.
Actions   Browse: longitudinal data    Spreadsheet: csv  |  xls    Images: ftp  |  web services